Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MRE11 | P49959 | 1/20 | 0.41 |
| ▸ | NAT1 | P18440 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714349 | 1.00 | GSK3B (0.50) | GSK3BMETAP1HPGDTDP1AKR1B1 | |
| SCHEMBL751633 | 1.00 | GSK3B (0.50) | GSK3BMETAP1HPGDTDP1AKR1B1 | |
| SCHEMBL3714215 | 0.78 | MAPT (0.54) | METAP1HPGDTDP1RAB9AALDH1A1 | |
| SCHEMBL3714214 | 0.78 | MAPT (0.54) | METAP1HPGDTDP1RAB9AALDH1A1 | |
| SCHEMBL132173 | 0.75 | GSK3B (0.50) | GSK3BMETAP1HPGDTDP1AKR1B1 | |
| SCHEMBL132172 | 0.75 | GSK3B (0.50) | GSK3BMETAP1HPGDTDP1AKR1B1 | |
| SCHEMBL3711176 | 0.75 | LRRK2 (0.41) | — | |
| Hydrogen Peroxide SCHEMBL29033947 | 0.74 | GSK3B (0.49) | GSK3BMETAP1HPGDTDP1AKR1B1 | |
| SCHEMBL29899807 | 0.72 | CLK1 (0.54) | GSK3BRAB9AMEN1KMT2AKDM4E | |
| SCHEMBL3720355 | 0.71 | IGF1R (0.51) | HPGDTDP1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130344591-A1 | Modified Fluorescent Proteins and Methods for Using Same | EVROGEN JSC (RU) | 2013-12-26 | — | — | US | disclosed |
| US-8481307-B2 | Modified fluorescent proteins and methods for using same | EVROGEN JSC (RU) | 2013-07-09 | — | — | US | disclosed |
| US-20120094377-A1 | Modified Fluorescent Proteins and Methods for Using Same | EVROGEN JSC (RU) | 2012-04-19 | — | — | US | disclosed |
| EP-2430156-A1 | MODIFIED FLUORESCENT PROTEINS AND METHODS FOR USING SAME | Evrogen Jsc (RU) | 2012-03-21 | — | — | EP | disclosed |
| US-7972834-B2 | Modified fluorescent proteins and methods for using same | Evrogen IP Joint Stock Company (RU) | 2011-07-05 | — | — | US | disclosed |
| US-20110003974-A1 | Modified fluorescent proteins and methods for using same | Evrogen IP Joint Stock Company (RU) | 2011-01-06 | — | — | US | disclosed |
| WO-2010131115-A1 | MODIFIED FLUORESCENT PROTEINS AND METHODS FOR USING SAME | EVROGEN JSC (RU) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010122426-A2 | METHODS AND COMPOSITIONS FOR VISUALIZATION OF FLUORESCENT PROTEINS | EVROGEN JSC (RU) | 2010-10-28 | — | — | WO | disclosed |