Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132173 | 1.00 | GSK3B (0.50) | GSK3BALDH1A1HPGDKMT2AMEN1 | |
| Hydrogen Peroxide SCHEMBL29033947 | 0.98 | GSK3B (0.49) | GSK3BALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL16111885 | 0.78 | MAPT (0.54) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL751632 | 0.75 | GSK3B (0.50) | GSK3BALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL751633 | 0.75 | GSK3B (0.50) | GSK3BALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3714349 | 0.75 | GSK3B (0.50) | GSK3BALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL15954810 | 0.75 | LRRK2 (0.38) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL16111649 | 0.71 | KMT2A (0.50) | GSK3BALDH1A1HPGDKMT2AMEN1 | |
| 4-Hydroxyphenylmethylene Hydantoin SCHEMBL5343815 | 0.67 | GSK3B (1.00) | GSK3BALDH1A1HPGDKMT2AMEN1 | |
| 4-Hydroxyphenylmethylene Hydantoin SCHEMBL5346095 | 0.67 | GSK3B (1.00) | GSK3BALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12436104-B2 | Fluorescent probe for branched chain amino acids and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-10-07 | — | — | US | disclosed |
| EP-3778650-B1 | FLUORESCENT PROBE FOR BRANCHED CHAIN AMINO ACIDS AND USE THEREOF | UNIV EAST CHINA SCIENCE & TECH (CN) | 2025-08-20 | — | — | EP | disclosed |
| US-20240027344-A1 | Fluorescent Probe for Branched Chain Amino Acids and Use Thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2024-01-25 | — | — | US | disclosed |
| US-20210094922-A1 | Dyes for Analysis of Soluble Protein Aggregates or Misfolded Protein Oligomers | PENN STATE RES FOUND (US) | 2021-04-01 | — | — | US | disclosed |
| EP-3778650-A1 | FLUORESCENT PROBE FOR BRANCHED CHAIN AMINO ACIDS AND USE THEREOF | East China University of Science and Technology (CN) | 2021-02-17 | — | — | EP | disclosed |
| EP-3761976-A1 | DYES FOR ANALYSIS OF SOLUBLE PROTEIN AGGREGATES OR MISFOLDED PROTEIN OLIGOMERS | The Penn State Research Foundation (US) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019174633-A1 | FLUORESCENT PROBE FOR BRANCHED CHAIN AMINO ACIDS AND USE THEREOF | 华东理工大学 | 2019-09-19 | — | — | WO | disclosed |
| WO-2019173607-A1 | DYES FOR ANALYSIS OF SOLUBLE PROTEIN AGGREGATES OR MISFOLDED PROTEIN OLIGOMERS | THE PENN STATE RESEARCH FOUNDATION (US) | 2019-09-12 | — | — | WO | disclosed |
| CN-108395484-A | Branched-chain amino acid fluorescence probe and its application | 华东理工大学 | 2018-08-14 | — | — | CN | disclosed |
| US-9945860-B2 | Nicotinamide adenine dinucleotide indicators, methods of preparation and application thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-04-17 | — | — | US | disclosed |
| US-20070254373-A1 | Fragments of fluorescent proteins for protein fragment complementation assays | ODYSSEY PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| US-7166424-B2 | Fragments of fluorescent proteins for protein fragment complementation assays | ODYSSEY THERA INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7001892-B1 | Pharmaceutical materials and methods for their preparation and use | PURDUE RESEARCH FOUNDATION (US) | 2006-02-21 | — | — | US | disclosed |
| US-20040229240-A1 | In vivo screening of protein-protein interactions with protein-fragment complementation assays | THE UNIVERSITY OF MONTREAL (CA) | 2004-11-18 | — | — | US | disclosed |
| US-20040137528-A1 | Fragments of fluorescent proteins for protein fragment complementation assays | ODYSSEY THERA INC. | 2004-07-15 | — | — | US | disclosed |
| WO-2000076480-A9 | PHARMACEUTICAL MATERIALS AND METHODS FOR THEIR PREPARATION AND USE | LILLY CO ELI (US) | 2002-07-11 | — | — | WO | disclosed |
| EP-1189599-A2 | PHARMACEUTICAL MATERIALS AND METHODS FOR THEIR PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000076480-A2 | PHARMACEUTICAL MATERIALS AND METHODS FOR THEIR PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| US-6020192-A | GENES ADAPTED FOR HIGH LEVEL EXPRESSION IN MAMMALIAN CELLS, ESPECIALLY THOSE OF HUMAN ORIGIN. | UNIVERSITY OF FLORIDA (US) | 2000-02-01 | — | — | US | disclosed |
| US-5874304-A | HIGH LEVEL EXPRESSION IN MAMMALIAN CELLS, ESPECIALLY OF HUMAN; BASE SUBSTITUTIONS MADE IN VARIOUS CODONS TO CHANGE THE CODON USAGE TO ONE MORE APPROPRIATE FOR EXPRESSION IN MAMMALS; GENE THERAPY; REPORTER GENE KITS; CELL DETECTION | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1999-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094922-A1 | Dyes for Analysis of Soluble Protein Aggregates or Misfolded Protein Oligomers | HSPBP1, HTT, HSPA5 | GSK3B 4514/4885ALDH1A1 4521/4885HPGD 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.