Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576312 | 0.85 | KCNH2 (0.53) | MAPTKDM4EALDH1A1MAPK1KCNH2 | |
| SCHEMBL3794785 | 0.76 | KCNH2 (0.38) | KCNH2HRH3LTA4HADRA2AADRA2B | |
| SCHEMBL959643 | 0.70 | — | — | |
| SCHEMBL3818350 | 0.68 | MAPT (0.47) | MAPTKDM4EALDH1A1MAPK1CA12 | |
| SCHEMBL7519297 | 0.68 | KCNH2 (0.34) | KCNH2HRH3LTA4HADRA2ASMN1; SMN2 | |
| SCHEMBL23576315 | 0.67 | KCNH2 (0.47) | MAPTKDM4EALDH1A1MAPK1KCNH2 | |
| SCHEMBL9862825 | 0.67 | KCNH2 (0.50) | MAPTKDM4EALDH1A1MAPK1KCNH2 | |
| SCHEMBL9862823 | 0.67 | KCNH2 (0.50) | MAPTKDM4EALDH1A1MAPK1KCNH2 | |
| SCHEMBL23309639 | 0.66 | KCNH2 (0.33) | KCNH2HRH3LTA4H | |
| SCHEMBL105809 | 0.65 | NPC1 (0.41) | KCNH2HRH3LTA4HADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174422-A2 | Environment-friendly process for the preparation of sterically hindered phenols with high molecular weight | Institut für Polymerforschung Dresden e.V. (DE) | 2002-01-23 | — | — | EP | disclosed |