SCHEMBL105809

SCHEMBL105809

c1cc(C2=NCCO2)cc(C2=NCCO2)c1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.41
KCNH2 Q12809 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
KCNN4 O15554 1/20 0.37
LTA4H P09960 1/20 0.37
NISCH Q9Y2I1 1/20 0.35
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20410845 0.96 NPC1 (0.39) NPC1KCNH2HRH3SMN1; SMN2KCNN4
SCHEMBL27260114 0.92 NISCH (0.46) NPC1SMN1; SMN2KCNN4NISCHADRA2A
SCHEMBL10520530 0.92 KCNH2 (0.38) NPC1KCNH2HRH3SMN1; SMN2LTA4H
Carbimide SCHEMBL29055881 0.92 NPC1 (0.37) NPC1KCNH2HRH3SMN1; SMN2KCNN4
SCHEMBL23054974 0.91 KCNH2 (0.37) NPC1KCNH2HRH3LTA4H
SCHEMBL20410958 0.91 L3MBTL1 (0.37) NPC1KCNH2HRH3SMN1; SMN2KCNN4
SCHEMBL1646929 0.88 NOS3 (0.39) NPC1KCNH2HRH3NISCH
SCHEMBL20409940 0.88 SMN1; SMN2 (0.40) NPC1KCNH2HRH3SMN1; SMN2KCNN4
SCHEMBL1338566 0.87 NISCH (0.47) NPC1SMN1; SMN2NISCH
SCHEMBL4751753 0.87 CHRNB4 (0.47) ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3160 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080375-A Polyester material, heat-shrinkable film, and preparation method and application thereof 2026-05-26 CN claimed
US-20260132251-A1 POLYALKYLENECARBONATE RESIN COMPOSITION AND METHOD FOR PREPARING THE SAME LG CHEM LTD (KR) 2026-05-14 US claimed
CN-122011609-A Insulation protective sleeve material for high-voltage cable and preparation method thereof 武汉市黄鹤电线电缆一厂有限公司 2026-05-12 CN claimed
CN-122011369-A Semi-aromatic polyamide resin and synthesis method thereof 广东中塑新材料股份有限公司 2026-05-12 CN claimed
CN-122013347-A High-quality copolymerized flame-retardant nylon 66 fiber and preparation method thereof 浙江理工大学 2026-05-12 CN claimed
US-12595364-B2 Thermoplastic resin composition for air intake hose with improved heat resistance and molded article comprising same HYUNDAI MOTOR COMPANY (KR) 2026-04-07 US claimed
US-12428525-B2 Thermoplastic composition made from a polyamide polymer obtained from a prepolymer and a chain extender and manufacturing method ARKEMA FRANCE (FR) 2025-09-30 US claimed
EP-4621114-A1 DEGRADABLE FILAMENT, PREPARATION METHOD THEREFOR, AND USE THEREOF Beijing Phabuilder Biotechnology Co., Ltd. (CN) 2025-09-24 EP claimed
US-12371560-B2 Regenerated alloy material based on chemical and physical co-modification and method for preparing same CHINA NATIONAL ELECTRIC APPARATUS RESEARCH INSTITUTE CO., LTD. (CN) 2025-07-29 US claimed
EP-4559961-A1 POLYALKYLENE CARBONATE RESIN COMPOSITION AND PREPARATION METHOD THEREFOR LG Chem, Ltd. (KR) 2025-05-28 EP claimed
EP-0284880-A2 Resins from phenolics and oxazolines using phosphine catalysts Ashland Oil, Inc. (US) 1988-10-05 EP claimed
EP-0282263-A2 Halogen-containing polyester resin composition and electric wire POLYPLASTICS CO. LTD. (JP) 1988-09-14 EP claimed
US-4748230-A Preparation of resin from phenolic and oxazoline using phosphine catalyst ASHLAND OIL, INC. (US) 1988-05-31 US claimed
US-4731398-A POLYESTER, POLYOXAZOLINE, ACRYLATE DYNAMIT NOBEL AG (DE) 1988-03-15 US claimed
EP-0149837-B1 HEAT HARDENABLE ADHESIVE AND CEMENT HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1988-03-02 EP claimed
EP-0250715-A1 Resins from phenolics and oxazolines using phosphorous acid esters as catalysts Ashland Oil, Inc. (US) 1988-01-07 EP claimed
US-4699970-A Resin from phenolic and oxazoline using phosphorous acid ester as catalyst ASHLAND OIL, INC. (US) 1987-10-13 US claimed
EP-0222165-A2 Heat-curable adhesive and sealing compounds HÜLS AKTIENGESELLSCHAFT (DE) 1987-05-20 EP claimed
US-4562225-A BLEND OF POLYESTERE AND POLYOXAZOLINES DYNAMIT NOBEL AG (DE) 1985-12-31 US claimed
EP-0149837-A2 Heat hardenable adhesive and cement HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1985-07-31 EP claimed