Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516738 | 0.91 | MAPT (0.62) | F10PRSS1PRSS2PRSS3SMN1; SMN2 | |
| SCHEMBL6387684 | 0.88 | F10 (0.83) | F10PRSS1PRSS2PRSS3SMN1; SMN2 | |
| SCHEMBL6390565 | 0.85 | F10 (0.63) | F10SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL6391954 | 0.82 | F10 (0.60) | F10SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL7518683 | 0.78 | F10 (0.77) | F10PRSS1PRSS2PRSS3SMN1; SMN2 | |
| SCHEMBL6388544 | 0.78 | F10 (0.55) | F10SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL6388548 | 0.78 | F10 (0.55) | F10SMN1; SMN2ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL7515588 | 0.78 | F10 (0.98) | F10PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL6389549 | 0.76 | F10 (0.53) | F10SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL29123955 | 0.76 | MAPT (0.72) | F10SMN1; SMN2ALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174421-A1 | 3-AMIDINOBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |