Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 8/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378378 | 0.92 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 | |
| SCHEMBL7751053 | 0.90 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7372942 | 0.90 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7373559 | 0.89 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 | |
| SCHEMBL7372097 | 0.89 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7370995 | 0.87 | AVPR2 (0.48) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 | |
| SCHEMBL7749486 | 0.86 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7371692 | 0.86 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 | |
| SCHEMBL7379386 | 0.86 | CYP1A2 (0.44) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 | |
| SCHEMBL7376322 | 0.85 | AVPR2 (0.51) | AVPR2AVPR1AAVPR1BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |