SCHEMBL751653

SCHEMBL751653

Brc1cccc(-c2nc3ccccc3o2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.68
NPC1 O15118 6/20 0.68
TP53 P04637 6/20 0.68
HSD17B10 Q99714 6/20 0.68
MEN1 O00255 5/20 0.68
KMT2A Q03164 5/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
MAPT P10636 4/20 0.68
RAB9A P51151 4/20 0.68
P2RY14 Q15391 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
TSHR P16473 2/20 0.56
ALDH1A1 P00352 5/20 0.55
HPGD P15428 3/20 0.55
PKM P14618 1/20 0.55
ATM Q13315 1/20 0.54
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
USP2 O75604 2/20 0.51
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29407133 1.00 KDM4E (0.68) KDM4ENPC1TP53HSD17B10MEN1
SCHEMBL376001 0.88 ALDH1A1 (0.64) KDM4ENPC1TP53HSD17B10MEN1
SCHEMBL15497749 0.86 NPC1 (0.57) KDM4ENPC1TP53HSD17B10MEN1
SCHEMBL2478700 0.86 NPC1 (0.57) KDM4ENPC1TP53HSD17B10MEN1
SCHEMBL12076741 0.86 ALDH1A1 (0.62) KDM4ENPC1TP53HSD17B10MEN1
SCHEMBL28870971 0.85 MEN1 (0.53) KDM4ENPC1TP53HSD17B10MEN1
SCHEMBL18875311 0.85 NPC1 (0.56) KDM4ENPC1TP53HSD17B10MEN1
SCHEMBL2841814 0.84 NPC1 (0.70) KDM4ENPC1TP53HSD17B10MEN1
SCHEMBL12376180 0.84 ALDH1A1 (0.60) KDM4ENPC1TP53HSD17B10MEN1
SCHEMBL19846155 0.84 KDM4E (0.57) KDM4ENPC1TP53HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11997870-B2 Organic electroluminescent element and method for producing same HODOGAYA CHEMICAL CO., LTD. (JP) 2024-05-28 US disclosed
EP-4207947-B1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME HODOGAYA CHEMICAL CO LTD (JP) 2024-03-13 EP disclosed
US-20230357219-A1 PREPARATION OF BIARYL RING-LINKED AROMATIC HETEROCYCLIC DERIVATIVE AS IMMUNOMODULATOR AND USE THEREOF SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD. (CN) 2023-11-09 US disclosed
US-20230322691-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-10-12 US disclosed
US-20230322691-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-10-12 US disclosed
US-20230309339-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
CN-111869326-B Organic electroluminescent element and method for manufacturing the same 保土谷化学工业株式会社 2023-09-26 CN disclosed
CN-113135923-B Composition for cover layer of organic electroluminescent device and organic electroluminescent device comprising same 伊爱尔安株式会社 2023-09-12 CN disclosed
US-11706943-B2 Organic electroluminescent element and method for producing same HODOGAYA CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
EP-4207947-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME Hodogaya Chemical Co., Ltd. (JP) 2023-07-05 EP disclosed
WO-2011097260-A1 TRIS (ARYLBENZOXAZOLE) BENZENE AND TRIS (ARYLBENZOTHIAZOLE) BENZENE AS ORGANIC ELECTRON - TRANS PORT MATERIALS NITTO DENKO CORPORATION (JP) 2011-08-11 WO disclosed
US-20110187969-A1 POLYMERIC LIGHT EMITTING SUBSTANCE AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-04 US disclosed
US-7947340-B2 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-24 US disclosed
EP-2258808-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
EP-2258807-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
EP-2258809-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
EP-2258805-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
EP-2258806-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
US-20020193532-A1 Comprises polystyrene and organometallic polymer; luminescence; for use in spin coating and ink jet printing SUMITOMO CHEMICAL COMPANY, LIMITED 2002-12-19 US disclosed
EP-1245659-A1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357219-A1 PREPARATION OF BIARYL RING-LINKED AROMATIC HETEROCYCLIC DERIVATIVE AS IMMUNOMODULATOR AND USE THEREOF PDCD1, CD274, PDCD1LG2 KDM4E 1370/4885NPC1 2221/4885TP53 64/4885
US-20230322691-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CCNT1, CCNE2, SCO2 KDM4E 3380/4885NPC1 1944/4885TP53 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.