Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512295 | 0.95 | CYSLTR1 (0.48) | CYSLTR1CYSLTR2 | |
| SCHEMBL9818413 | 0.92 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2 | |
| SCHEMBL7520309 | 0.92 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2 | |
| SCHEMBL7717000 | 0.90 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2 | |
| SCHEMBL10534084 | 0.90 | CYSLTR2 (0.47) | CYSLTR1CYSLTR2 | |
| SCHEMBL7518817 | 0.90 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2 | |
| SCHEMBL7551982 | 0.90 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2 | |
| SCHEMBL7516263 | 0.89 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2 | |
| SCHEMBL7715810 | 0.88 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2 | |
| SCHEMBL7513912 | 0.88 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030665-A4 | THERAPEUTIC USES OF QUINOLINE DERIVATIVES | AVENTIS PHARM PROD INC (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6376512-B1 | FOR TREATING PHYSIOLOGICAL CONDITION IN PATIENT WHEREIN SAID CONDITION IS ASSOCIATED WITH A PHYSIOLOGICALLY DETRIMENTAL LEVELS OF INSULIN, GLUCOSE, FREE FATTY ACIDS, OR TRIGLYCERIDES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-23 | — | — | US | disclosed |
| EP-1030665-A1 | THERAPEUTIC USES OF QUINOLINE DERIVATIVES | Aventis Pharmaceuticals Products Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999020275-A1 | THERAPEUTIC USES OF QUINOLINE DERIVATIVES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-04-29 | — | — | WO | disclosed |
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |