Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1382964 | 0.91 | AADAT (0.41) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1384479 | 0.87 | PIM1 (0.44) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7593551 | 0.87 | PIM1 (0.44) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4502759 | 0.86 | PIM1 (0.43) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4519527 | 0.84 | KCNH2 (0.46) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4501229 | 0.83 | KCNH2 (0.45) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7514311 | 0.81 | SIRT2 (0.38) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14444889 | 0.81 | AADAT (0.38) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5459852 | 0.81 | AADAT (0.38) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14444384 | 0.79 | AADAT (0.36) | AADATKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |