Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511000 | 0.84 | — | — | |
| SCHEMBL7508801 | 0.78 | CA2 (0.39) | CA2CA4CA12CA1CA6 | |
| SCHEMBL9536622 | 0.75 | — | — | |
| SCHEMBL12603504 | 0.75 | CA2 (0.41) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8950242 | 0.75 | CA2 (0.33) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8950462 | 0.74 | CA2 (0.37) | CA2CA4CA12CA1CA6 | |
| SCHEMBL3586845 | 0.71 | CA2 (0.47) | CA2CA4CA12CA1CA6 | |
| SCHEMBL3585070 | 0.71 | CA2 (0.47) | CA2CA4CA12CA1CA6 | |
| SCHEMBL3577810 | 0.71 | CA2 (0.47) | CA2CA4CA12CA1CA6 | |
| SCHEMBL18651229 | 0.71 | CA2 (0.45) | CA2CA4CA12CA1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527801-B1 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANHYDRASE INHIBITORS | ALCON LAB INC (US) | 2002-07-31 | — | — | EP | disclosed |
| US-5240923-A | Treating glaucoma | ALCON LABORATORIES, INC. (US) | 1993-08-31 | — | — | US | disclosed |