Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17740480 | 0.88 | NPC1 (0.45) | NPC1MAPTCASP3RAB9ASMN1; SMN2 | |
| SCHEMBL17740485 | 0.86 | RARB (0.43) | NPC1MAPTCASP3RAB9ASMN1; SMN2 | |
| SCHEMBL16922710 | 0.85 | SRD5A2 (0.40) | MAOBMAOASRD5A2 | |
| SCHEMBL17740479 | 0.83 | RARA (0.46) | NPC1MAOBRARARARB | |
| SCHEMBL8051851 | 0.82 | NPC1 (0.40) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6566277 | 0.80 | MAPT (0.34) | NPC1MAPTCASP3RAB9ASMN1; SMN2 | |
| SCHEMBL6566269 | 0.80 | MAPT (0.34) | NPC1MAPTCASP3RAB9ASMN1; SMN2 | |
| SCHEMBL18499559 | 0.79 | ESR1 (0.47) | NPC1MAPTCASP3RAB9ASMN1; SMN2 | |
| SCHEMBL8051871 | 0.79 | RARB (0.40) | NPC1MAPTSMN1; SMN2RARARARB | |
| SCHEMBL9762731 | 0.79 | PARP10 (0.35) | NPC1MAPTCASP3RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738709-B1 | Ester derivate, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2002-01-23 | — | — | EP | disclosed |
| EP-1010687-A2 | Ester derivative, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 2000-06-21 | — | — | EP | disclosed |
| US-5755994-A | LARGE DIELECTRIC ANISOTROPIC | CHISSO CORPORATION (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0738709-A2 | Ester derivate, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-10-23 | — | — | EP | disclosed |