Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871594 | 1.00 | ENPP2 (0.48) | ENPP2ALDH1A1CYP1A1CYP1A2CYP1B1 | |
| Benzene SCHEMBL28804146 | 1.00 | ENPP2 (0.48) | ENPP2ALDH1A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1331365 | 1.00 | — | — | |
| Water SCHEMBL27932616 | 1.00 | ENPP2 (0.48) | ENPP2ALDH1A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL37831 | 1.00 | — | — | |
| SCHEMBL31402005 | 1.00 | — | — | |
| SCHEMBL1332411 | 1.00 | — | — | |
| SCHEMBL1921814 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28747248 | 0.97 | ENPP2 (0.47) | ENPP2ALDH1A1CYP1A1CYP1A2CYP1B1 | |
| Hydrochloric Acid SCHEMBL4699655 | 0.97 | ENPP2 (0.47) | ENPP2ALDH1A1CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093861-C | 1-methylcarbapenem derivatives | SANKYO CO (JP) | 2002-11-06 | — | — | CN | disclosed |
| EP-0900797-B1 | A 1-METHYLCARBAPENEM DERIVATIVE | SANKYO CO (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| CN-1223655-A | 1-methylcarbapenem derivatives | SANKYO CO (JP) | 1999-07-21 | — | — | CN | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |