Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 5/20 | 0.47 |
| ▸ | HTR1B | P28222 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6347317 | 0.90 | HTR1A (0.51) | HTR1DHTR1B | |
| SCHEMBL6354568 | 0.81 | HTR1D (0.57) | HTR1DHTR1B | |
| SCHEMBL7845970 | 0.72 | KMT2A (0.58) | DRD4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6348488 | 0.72 | HTR1D (0.57) | HTR1DHTR1B | |
| SCHEMBL6342285 | 0.70 | HTR1A (0.64) | HTR1DHTR1B | |
| SCHEMBL5341488 | 0.70 | HDAC1 (0.59) | MEN1KMT2AALDH1A1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL6342480 | 0.69 | HTR1A (0.62) | HTR1DHTR1B | |
| SCHEMBL5345178 | 0.69 | MEN1 (0.56) | MEN1KMT2AALDH1A1KDM4EBRD4 | |
| SCHEMBL27707244 | 0.69 | KDM4E (0.64) | KMT2AALDH1A1KDM4EBRD4POLB | |
| SCHEMBL7092859 | 0.69 | HRH2 (0.61) | MEN1KMT2AALDH1A1KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140898-B1 | AMIDE AND UREA DERIVATIVES AS 5-HT REUPTAKE INHIBITORS AND AS 5-HT1B/1D LIGANDS | MERCK PATENT GMBH (DE) | 2002-08-28 | — | — | EP | disclosed |