Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 6/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726787 | 0.87 | ACACB (0.46) | ACACBCA2CA1NAMPTNR1H4 | |
| SCHEMBL21523879 | 0.86 | NPC1 (0.64) | NAMPTNR1H4NPC1RAB9APOLB | |
| SCHEMBL29023020 | 0.85 | CA2 (0.48) | ACACBCA2CA1NAMPTNPC1 | |
| SCHEMBL8757522 | 0.84 | GLA (0.67) | CA2CA1NAMPTKDM4ENPC1 | |
| SCHEMBL8757517 | 0.83 | CA2 (0.53) | CA2CA1NAMPTNPC1RAB9A | |
| SCHEMBL25674677 | 0.83 | CA2 (0.53) | CA2CA1NAMPTKDM4ERAB9A | |
| SCHEMBL11687632 | 0.82 | NPC1 (0.56) | CA2CA1NAMPTKDM4ENPC1 | |
| SCHEMBL27741033 | 0.82 | ACACB (0.59) | ACACBCA2CA1NAMPTNR1H4 | |
| SCHEMBL1295461 | 0.81 | POLB (0.52) | ACACBCA2CA1NR1H4KDM4E | |
| SCHEMBL1569661 | 0.81 | CA2 (0.56) | CA2CA1NAMPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174421-A1 | 3-AMIDINOBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |