SCHEMBL7517893

SCHEMBL7517893

CCCCC(C)(C)C(C)(C)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
EPHX1 P07099 1/20 0.35
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
ATM Q13315 1/20 0.35
TSHR P16473 3/20 0.35
KDM4E B2RXH2 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
ACAT1 P24752 1/20 0.35
SOAT1 P35610 1/20 0.35
DGAT1 O75907 1/20 0.34
ALDH1A1 P00352 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5797151 0.92 MAPT (0.44) EPHX1CYP4F2CYP4A11L3MBTL1MAPT
SCHEMBL23199993 0.92 MAPT (0.44) EPHX1CYP4F2CYP4A11L3MBTL1MAPT
SCHEMBL11048521 0.92 MAPT (0.44) EPHX1CYP4F2CYP4A11L3MBTL1MAPT
SCHEMBL27916266 0.85 CA1 (0.42) CA1CA2EPHX1CYP4F2CYP4A11
SCHEMBL1245575 0.83 CYP4F2 (0.46) CA1CA2EPHX1CYP4F2CYP4A11
SCHEMBL28587030 0.81 MAPT (0.41) EPHX1L3MBTL1MAPTKMT2AMEN1
Hydrochloric Acid SCHEMBL28814883 0.81 CYP4F2 (0.44) CA1CA2EPHX1CYP4F2CYP4A11
SCHEMBL28117442 0.81 CYP4F2 (0.44) CA1CA2EPHX1CYP4F2CYP4A11
SCHEMBL27916314 0.81 ALDH1A1 (0.39) CA1CA2EPHX1CYP4F2CYP4A11
SCHEMBL27516637 0.81 CYP4F2 (0.44) CA1CA2EPHX1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1196445-A1 INSULIN CRYSTALS FOR PULMONARY ADMINISTRATION ELI LILLY AND COMPANY (US) 2002-04-17 EP disclosed
EP-1173482-A1 INSULIN CRYSTALS FOR PULMONARY ADMINISTRATION ELI LILLY AND COMPANY (US) 2002-01-23 EP disclosed
WO-2001000674-A1 INSULIN CRYSTALS FOR PULMONARY ADMINISTRATION ELI LILLY AND COMPANY (US) 2001-01-04 WO disclosed
WO-2000064940-A1 INSULIN CRYSTALS FOR PULMONARY ADMINISTRATION ELI LILLY AND COMPANY (US) 2000-11-02 WO disclosed