Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525234 | 0.94 | TSHR (0.41) | ADRB2ADRB1ADRB3ALDH1A1CYP2C19 | |
| SCHEMBL30727333 | 0.83 | TSHR (0.49) | ALDH1A1TSHRTDP1KMT2AMEN1 | |
| SCHEMBL1185010 | 0.83 | TSHR (0.49) | ALDH1A1TSHRTDP1KMT2AMEN1 | |
| SCHEMBL223562 | 0.82 | LMNA (0.51) | ALDH1A1CYP2C19TDP1KMT2ANPC1 | |
| SCHEMBL7006661 | 0.82 | MAPT (0.50) | ALDH1A1CYP2C19TDP1KMT2ANPC1 | |
| SCHEMBL5103038 | 0.81 | S1PR4 (0.41) | ALDH1A1CYP2C19TSHRTDP1KMT2A | |
| SCHEMBL7520954 | 0.81 | TSHR (0.42) | ALDH1A1CYP2C19TSHRTDP1KMT2A | |
| SCHEMBL30326242 | 0.80 | S1PR4 (0.40) | ALDH1A1CYP2C19TSHRTDP1KMT2A | |
| SCHEMBL12134869 | 0.80 | CYP19A1 (0.42) | ALDH1A1CYP2C19TSHRTDP1KMT2A | |
| SCHEMBL2909665 | 0.80 | MAPT (0.44) | ALDH1A1CYP2C19TSHRTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |