Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518517 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1FPR2MAPK1POLB | |
| SCHEMBL7514492 | 0.78 | MME (0.41) | SMN1; SMN2ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL7514485 | 0.78 | MME (0.41) | SMN1; SMN2ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL10792981 | 0.76 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1FPR2MAPK1POLB | |
| SCHEMBL205860 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1FPR2MAPK1POLB | |
| SCHEMBL748887 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1FPR2MAPK1POLB | |
| SCHEMBL13530960 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1FPR2MAPK1POLB | |
| SCHEMBL14389451 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1FPR2MAPK1POLB | |
| SCHEMBL9717667 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1FPR2MAPK1POLB | |
| SCHEMBL8752641 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1FPR2MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041082-B1 | Process of peptidic synthesis starting from N-carboxyanhydride amino acids | DEGUSSA (DE) | 2002-04-17 | — | — | EP | disclosed |
| EP-0787137-B1 | PROCESS FOR THE PREPARATION OF N-CARBOXYANHYDRIDE AMINO ACIDS FROM N-(N'-NITROSOCARBAMOYL)AMINO ACIDS | DEGUSSA (DE) | 2002-01-23 | — | — | EP | disclosed |
| EP-1041082-A1 | Process of peptidic synthesis starting from N-carboxyanhydride amino acids | Degussa-Hüls Aktiengesellschaft (DE) | 2000-10-04 | — | — | EP | disclosed |
| US-5777076-A | Method for peptide synthesis starting from N- (N'-nitrosocarbamoyl) amino acids | UNIVERSITE MONTPELLIER II SCIENCES ET TECHNIQUES DU LANGUEDOC (FR) | 1998-07-07 | — | — | US | disclosed |
| EP-0787137-A2 | METHOD FOR PEPTIDE SYNTHESIS BASED ON N-(N'-NITROSOCARBAMOYL)AMINO ACIDS | UNIVERSITE MONTPELLIER II SCIENCES ET TECHNIQUES DU LANGUEDOC (FR) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996012729-A2 | METHOD FOR PEPTIDE SYNTHESIS BASED ON N-(N'-NITROSOCARBAMOYL)AMINO ACIDS | UNIVERSITE MONTPELLIER II SCIENCES ET TECHNIQUES DU LANGUEDOC (FR) | 1996-05-02 | — | — | WO | disclosed |