Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25673004 | 0.81 | RET (0.60) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| SCHEMBL25673083 | 0.76 | IDO1 (0.76) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| SCHEMBL30915484 | 0.76 | IDO1 (0.56) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| SCHEMBL29352087 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| SCHEMBL28547458 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| SCHEMBL24115843 | 0.75 | RET (0.77) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| SCHEMBL29843330 | 0.75 | RET (0.77) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| SCHEMBL29367518 | 0.75 | RET (0.77) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| SCHEMBL3362960 | 0.75 | RET (0.77) | SMN1; SMN2KDM4ELMNAMAPTHPGD | |
| SCHEMBL130234 | 0.75 | RET (0.77) | SMN1; SMN2KDM4ELMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743311-B1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5702691-A | Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives | KAO CORPORATION (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0743311-A1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1996-11-20 | — | — | EP | disclosed |