Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29352087 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 | |
| SCHEMBL28543921 | 0.87 | LMNA (0.54) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 | |
| SCHEMBL29101712 | 0.82 | ALDH1A1 (0.69) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 | |
| SCHEMBL7518815 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 | |
| SCHEMBL11111994 | 0.69 | DNMT3B (0.42) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 | |
| SCHEMBL24115843 | 0.69 | RET (0.77) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 | |
| SCHEMBL29367518 | 0.69 | RET (0.77) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 | |
| SCHEMBL3362960 | 0.69 | RET (0.77) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 | |
| SCHEMBL29843330 | 0.69 | RET (0.77) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 | |
| SCHEMBL3439134 | 0.69 | RET (0.77) | SMN1; SMN2KDM4ECYP2C19HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925427-B | Application of rice OsT5H gene as negative regulatory factor in promoting rice thrombosis | 浙江大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-111925427-A | Application of rice OsT5H gene as negative regulatory factor in promoting rice thrombosis | 浙江大学 | 2020-11-13 | — | — | CN | disclosed |