Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518634 | 0.88 | PARP1 (0.48) | PARP1PARP2 | |
| SCHEMBL3988137 | 0.87 | PARP1 (0.47) | PARP1 | |
| SCHEMBL6782694 | 0.83 | PARP1 (0.67) | PARP1PARP2 | |
| SCHEMBL7524922 | 0.81 | PARP1 (0.55) | PARP1PARP2 | |
| SCHEMBL7516631 | 0.80 | PARP1 (0.47) | PARP1PARP2 | |
| SCHEMBL6869338 | 0.79 | PARP1 (0.69) | PARP1PARP2 | |
| SCHEMBL7043962 | 0.79 | PARP1 (0.47) | PARP1PARP2 | |
| SCHEMBL7525305 | 0.79 | PARP1 (0.55) | PARP1PARP2 | |
| SCHEMBL3992291 | 0.79 | PARP1 (0.55) | PARP1PARP2 | |
| SCHEMBL7522321 | 0.79 | PARP1 (0.55) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171424-A1 | CYCLO-ALKYL SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS PARP INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000064878-A1 | CYCLO-ALKYL SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS PARP INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-02 | — | — | WO | disclosed |