⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779901 | 0.86 | MGAM (0.48) | — | |
| SCHEMBL53913 | 0.79 | — | — | |
| SCHEMBL3441102 | 0.79 | MGAM (0.69) | — | |
| Propionamide SCHEMBL28260391 | 0.77 | TSHR (0.48) | — | |
| SCHEMBL5411221 | 0.77 | — | — | |
| SCHEMBL6040697 | 0.77 | — | — | |
| SCHEMBL3074680 | 0.77 | — | — | |
| SCHEMBL8391853 | 0.77 | MGAM (0.50) | — | |
| SCHEMBL2977827 | 0.77 | — | — | |
| SCHEMBL708003 | 0.76 | MGAM (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192646-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2023-06-22 | — | — | US | claimed |
| EP-4081299-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2022-11-02 | — | — | EP | claimed |
| WO-2021130255-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2021-07-01 | — | — | WO | claimed |
| CN-102911175-B | Preparation method of 2-amino-4-carbonyl-7-(3,4-dimethoxybenzyl)-5-vinyl-6,7-dihydro-3H-pyrrolo-[2,3-d]pyrimidine | NANJING EAST SUNSCREEN PHARMACEUTICAL CO LTD | 2015-04-15 | — | — | CN | claimed |
| CN-102911175-A | Preparation method of 2-amino-4-carbonyl-7-(3,4-dimethoxybenzyl)-5-vinyl-6,7-dihydro-3H-pyrrolo-[2,3-d]pyrimidine | NANJING EAST SUNSCREEN PHARMACEUTICAL CO LTD | 2013-02-06 | — | — | CN | claimed |
| CN-101215261-B | Method for synthesizing of 2-oxo-3-pyridine formic acid ester and derivatives thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2011-09-07 | — | — | CN | claimed |
| CN-101790374-A | Use of kncq potassium channel openers for reducing symptoms of or treating disorders or conditions wherein the dopaminergic system is disrupted | LUNDBECK & CO AS H | 2010-07-28 | — | — | CN | claimed |
| US-20100163070-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE | L'OREAL S.A. (FR) | 2010-07-01 | — | — | US | claimed |
| CN-101384599-A | Heterocyclic antiviral compounds | HOFFMANN LA ROCHE (CH) | 2009-03-11 | — | — | CN | claimed |
| CN-101215261-A | Method for synthesizing of 2-oxo-3-pyridine formic acid ester and derivatives thereof | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2008-07-09 | — | — | CN | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| CN-1468226-A | Biphenyl derivatives and their use as ppar-gamma receptor activators | �������о�����չ˽������˾ | 2004-01-14 | — | — | CN | claimed |
| US-6676926-B2 | FOR ADMINISTERING TO A HUMAN IN NEED OF SUCH DIAGNOSIS AND MEASURING THE RADIOACTIVITY ARISING FROM THE ADMINISTRATION OF THE COMPOUND TO THE HUMAN EITHER BY USING A GAMMA CAMERA OR BY POSITRON EMISSION TOMOGRAPHY | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | claimed |
| CN-1422246-A | Malonamic acids and derivatives thereof as thyroid receptor ligands | PFIZER PROD INC (US) | 2003-06-04 | — | — | CN | claimed |
| US-6248571-B1 | USING RHODOCOCCUS TO CONVERT STARTING MATERIAL INTO MALONIC ACID DERVIATIVE, THEN CYCLIZING WITH CARBOXAMIDE IN PRESENCE OF BASE; CHEMICAL INTERMEDIATES FOR INSECTICIDES | LONZA AG (CH) | 2001-06-19 | — | — | US | claimed |
| EP-0001914-B1 | ANTIBACTERIALLY ACTIVE AMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID AMIDES | BEECHAM GROUP PLC (GB) | 1981-05-20 | — | — | EP | claimed |
| US-4200635-A | MONIC ACID A AMIDES | BEECHAM GROUP LIMITED (GB) | 1980-04-29 | — | — | US | claimed |
| EP-0001914-A2 | Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides | BEECHAM GROUP PLC (GB) | 1979-05-16 | — | — | EP | claimed |