Betamethasone Dipropionate

Betamethasone Dipropionate

SCHEMBL7519

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Betamethasone Dipropionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 known ✓ P04150 7/20 1.00
PGR P06401 5/20 1.00
NR1I2 O75469 2/20 1.00
MAPT P10636 2/20 1.00
ADORA3 P0DMS8 2/20 1.00
DRD2 P14416 1/20 1.00
OPRD1 P41143 1/20 1.00
CYP3A4 P08684 6/20 0.84
USP2 O75604 5/20 0.84
LMNA P02545 3/20 0.84
SMN1; SMN2 Q16637 2/20 0.84
CYP2C9 P11712 2/20 0.84
MLNR O43193 1/20 0.84
ABCB11 O95342 1/20 0.84
CYP3A5 P20815 1/20 0.84
PPARG P37231 1/20 0.84
NPSR1 Q6W5P4 1/20 0.84
CYP2D6 P10635 1/20 0.84
HIF1A Q16665 3/20 0.80
CNR1 P21554 2/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Betamethasone Dipropionate SCHEMBL14339597 1.00 NR3C1 (1.00) NR3C1PGRNR1I2MAPTADORA3
Betamethasone Dipropionate SCHEMBL4566 1.00 NR3C1 (1.00) NR3C1PGRNR1I2MAPTADORA3
Betamethasone Dipropionate SCHEMBL13028946 1.00 NR3C1 (1.00) NR3C1PGRNR1I2MAPTADORA3
Betamethasone Dipropionate SCHEMBL11429865 1.00 NR3C1 (1.00) NR3C1PGRNR1I2MAPTADORA3
Betamethasone Dipropionate SCHEMBL10014288 1.00 NR3C1 (1.00) NR3C1PGRNR1I2MAPTADORA3
Betamethasone Dipropionate SCHEMBL9768468 1.00 NR3C1 (1.00) NR3C1PGRNR1I2MAPTADORA3
Betamethasone Dipropionate SCHEMBL20097870 1.00 NR3C1 (1.00) NR3C1PGRNR1I2MAPTADORA3
Dexamethasone Dipropionate SCHEMBL43107 1.00 NR3C1 (1.00) NR3C1PGRNR1I2MAPTADORA3
Betamethasone Dipropionate SCHEMBL10013893 1.00 NR3C1 (1.00) NR3C1PGRNR1I2MAPTADORA3
Betamethasone Dipropionate SCHEMBL14141601 0.99 NR3C1 (0.98) NR3C1PGRNR1I2MAPTADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14168 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
EP-4744657-A1 THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF National University Corporation Okayama University (JP) 2026-05-20 EP claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2026-04-16 US claimed
EP-4724040-A1 TREATMENT OF PSORIASIS TRADOVA (PTY) LTD (ZA) 2026-04-15 EP claimed
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
EP-4680231-A1 USE OF ORAL JAK KINASE INHIBITORS TO TREAT LICHEN PLANUS Mayo Foundation for Medical Education and Research (US) 2026-01-21 EP claimed
EP-4301343-B1 PHARMACEUTICAL COMPOSITIONS WITH REDUCED SIDE EFFECT AND METHODS OF USING THE SAME TLC BIOPHARMACEUTICALS INC (US) 2025-11-19 EP claimed
US-20250319104-A1 MOISTURIZING CREAM FOR RADIATION DERMATITIS PERRY ARTHUR W (US) 2025-10-16 US claimed
US-12440499-B2 Topical composition MC2 Therapeutics Limited (GB) 2025-10-14 US claimed
EP-0049468-B1 ANTIFUNGAL COMPOSITIONS COMPRISING AN ANTIFUNGAL AGENT AND A CORTICOSTEROID SCHERING CORPORATION (US) 1984-05-16 EP claimed
EP-0097374-A2 Corticosteroid topical preparation SHIONOGI & CO., LTD. (JP) 1984-01-04 EP claimed
EP-0085334-A2 Substantive topical compositions PLOUGH, INC. (a Delaware corporation) (US) 1983-08-10 EP claimed
US-4370322-A BETAMETHASONE, BECLOMETHASONE AND CLOBETASOL DERIVATIVES GLAXO GROUP LIMITED (GB) 1983-01-25 US claimed
EP-0068553-A1 Topical antimicrobial anti-inflammatory compositions THE PROCTER & GAMBLE COMPANY (US) 1983-01-05 EP claimed
US-4343798-A Topical antimicrobial anti-inflammatory compositions THE PROCTER & GAMBLE COMPANY (US) 1982-08-10 US claimed
EP-0049468-A1 Antifungal compositions comprising an antifungal agent and a corticosteroid SCHERING CORPORATION (US) 1982-04-14 EP claimed
US-4298604-A FUNGICIDES, ANTIINFLAMMATORY AGENTS SCHERING CORPORATION (US) 1981-11-03 US claimed
US-4279900-A ANTIINFLAMMATORY INTREX RESEARCH CORPORATION (US) 1981-07-21 US claimed
US-4070462-A Steroid ointment SCHERING CORPORATION (US) 1978-01-24 US claimed