SCHEMBL7519280

SCHEMBL7519280

CC1(C)Sc2cc3c(cc2S1)SC(C)(C)S3

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19418333 0.58
SCHEMBL1292143 0.55
SCHEMBL14763863 0.47
SCHEMBL15323663 0.47
SCHEMBL10493360 0.46 VHL (0.30)
SCHEMBL11565768 0.42
SCHEMBL12434602 0.42
SCHEMBL12375831 0.42
SCHEMBL321091 0.40
SCHEMBL341533 0.38 ALDH1A1 (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2872520-B1 TRIARYLMETHYL RADICALS BRACCO IMAGING SPA (IT) 2016-09-14 EP disclosed
EP-2872520-B1 TRIARYLMETHYL RADICALS BRACCO IMAGING SPA (IT) 2016-09-14 EP disclosed
US-9381257-B2 Triarylmethyl radicals BRACCO IMAGING S.P.A. (IT) 2016-07-05 US disclosed
US-9381257-B2 Triarylmethyl radicals BRACCO IMAGING S.P.A. (IT) 2016-07-05 US disclosed
US-20150151009-A1 TRIARYLMETHYL RADICALS BRACCO IMAGING S.P.A. (IT) 2015-06-04 US disclosed
US-20150151009-A1 TRIARYLMETHYL RADICALS BRACCO IMAGING S.P.A. (IT) 2015-06-04 US disclosed
WO-2014009240-A1 TRIARYLMETHYL RADICALS BRACCO IMAGING SPA (IT) 2014-01-16 WO disclosed
EP-0871896-B1 A METHOD OF DETERMINING OXYGEN CONCENTRATION IN A SAMPLE NYCOMED IMAGING AS (NO) 2002-01-30 EP disclosed
US-6256527-B1 Method for determining oxygen concentration NYCOMED IMAGING AS (NO) 2001-07-03 US disclosed
EP-0832054-B1 HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS NYCOMED IMAGING AS (NO) 2000-12-27 EP disclosed
US-6063360-A USEFUL AS CONTRAST AGENT FOR OVERHAUSER MAGNETIC RESONACE IMAGING NYCOMED IMAGING A/S (NO) 2000-05-16 US disclosed
EP-0832054-A1 HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS NYCOMED IMAGING AS (NO) 1998-04-01 EP disclosed
EP-0662004-B1 USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING NYCOMED INNOVATION AB (SE) 1998-03-18 EP disclosed
US-5599522-A CONTRAST ENHANCING AGENTS NYCOMED IMAGING AS (NO) 1997-02-04 US disclosed
WO-1996039367-A1 HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS NYCOMED IMAGING A/S (NO) 1996-12-12 WO disclosed
US-5530140-A Free radicals NYCOMED IMAGING AS (NO) 1996-06-25 US disclosed
EP-0515458-B1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI NYCOMED INNOVATION AB (SE) 1995-08-23 EP disclosed
US-5435991-A Use of persistent heterocyclic free-radicals in magnetic resonance imaging NYCOMED INNOVATION AB (SE) 1995-07-25 US disclosed
EP-0515458-A1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI. HAFSLUND NYCOMED INNOVATION (SE) 1992-12-02 EP disclosed
WO-1991012024-A1 TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI HAFSLUND NYCOMED INNOVATION AB (SE) 1991-08-22 WO disclosed