Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.70 |
| ▸ | NAE1 | Q13564 | 3/20 | 0.39 |
| ▸ | UBA3 | Q8TBC4 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519494 | 1.00 | P2RY12 (0.70) | P2RY12NAE1UBA3 | |
| SCHEMBL7519132 | 0.85 | P2RY12 (0.51) | P2RY12NAE1UBA3 | |
| SCHEMBL6995281 | 0.82 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL6995290 | 0.82 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL7512903 | 0.79 | P2RY12 (0.78) | P2RY12NAE1UBA3 | |
| SCHEMBL7512896 | 0.79 | P2RY12 (0.78) | P2RY12NAE1UBA3 | |
| SCHEMBL7506130 | 0.79 | P2RY12 (0.53) | P2RY12 | |
| SCHEMBL7506139 | 0.79 | P2RY12 (0.53) | P2RY12 | |
| SCHEMBL7516058 | 0.79 | P2RY12 (0.77) | P2RY12NAE1UBA3 | |
| SCHEMBL7516050 | 0.79 | P2RY12 (0.77) | P2RY12NAE1UBA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946561-B1 | TRIAZOLO(4,5-D)PYRIMIDINYL DERIVATIVES AND THEIR USE AS MEDICAMENTS | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| US-6297232-B1 | TREATMENT OF PLATELET AGGREGATION DISORDERS. | ASTRAZENECA AB (SE) | 2001-10-02 | — | — | US | disclosed |