Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701511 | 0.88 | — | — | |
| SCHEMBL30040317 | 0.69 | — | — | |
| SCHEMBL743262 | 0.68 | — | — | |
| SCHEMBL14974813 | 0.65 | — | — | |
| SCHEMBL15787046 | 0.65 | — | — | |
| Methylamine SCHEMBL8761530 | 0.64 | — | — | |
| SCHEMBL6105380 | 0.64 | — | — | |
| SCHEMBL419917 | 0.64 | CCR2 (0.31) | — | |
| SCHEMBL30295004 | 0.63 | — | — | |
| SCHEMBL29187917 | 0.63 | HRH4 (0.32) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020161022-A1 | Indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation | AGOURON PHARMACEUTICALS | 2002-10-31 | — | — | US | disclosed |
| EP-0211584-A1 | Antihypertensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-02-25 | — | — | EP | disclosed |
| US-4618678-A | 4-(2,3-dichloro-6-fluorophenyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-1,7-naphthyridine-3-carboxylic acid 2-(2,3-dichlorophenoxy)ethyl ester | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |
| US-4596873-A | 1,4,5,6,7,8-Hexahydro-2-alkyl-4-aryl-5-oxo-1,7-naphthyridine-3-carboxylic acid aromatic esters and pharmaceutically acceptable acid addition salts thereof useful as antihypertensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161022-A1 | Indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation | CDK3, MKI67, ROCK1 | NISCH 2369/4885HRH4 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.