Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524618 | 1.00 | TDP1 (0.56) | TDP1TSHRTP53LMNAL3MBTL1 | |
| SCHEMBL7519675 | 1.00 | TDP1 (0.56) | TDP1TSHRTP53LMNAL3MBTL1 | |
| SCHEMBL7524577 | 1.00 | TDP1 (0.56) | TDP1TSHRTP53LMNAL3MBTL1 | |
| SCHEMBL7513958 | 0.87 | TP53 (0.71) | TDP1TSHRTP53 | |
| SCHEMBL7513953 | 0.87 | TP53 (0.71) | TDP1TSHRTP53 | |
| SCHEMBL7513955 | 0.87 | TP53 (0.71) | TDP1TSHRTP53 | |
| SCHEMBL7518653 | 0.87 | TP53 (0.71) | TDP1TSHRTP53 | |
| SCHEMBL7523003 | 0.87 | TP53 (0.71) | TDP1TSHRTP53 | |
| SCHEMBL7517922 | 0.85 | TDP1 (0.50) | TDP1TSHRTP53LMNAL3MBTL1 | |
| SCHEMBL7521052 | 0.85 | TDP1 (0.50) | TDP1TSHRTP53LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020042055-A1 | Alteration of hydrolase genes and screening of the resulting libraries for the ability to catalyze specific reactions | MAXYGEN, INC. | 2002-04-11 | — | — | US | disclosed |
| WO-2001046476-A1 | ALTERATION OF HYDROLASE GENES AND SCREENING OF THE RESULTING LIBRARIES FOR THE ABILITY TO CATALYZE SPECIFIC REACTIONS | MAXYGEN, INC. (US) | 2001-06-28 | — | — | WO | disclosed |