SCHEMBL751992

SCHEMBL751992

CCCC(CC)(OC(C)=O)P(=O)(O)O

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 14/20 0.43
GAA P10253 1/20 0.38
GGPS1 O95749 7/20 0.35
SMPD1 P17405 2/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10630314 0.82 FDPS (0.42) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL4874702 0.82 FDPS (0.38) FDPSGGPS1
SCHEMBL2044769 0.77 GGPS1 (0.55) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL899070 0.75 FDPS (0.46) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL14955866 0.73 FDPS (0.41) FDPSGGPS1
SCHEMBL14675467 0.72 FDPS (0.52) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL2466613 0.71 GAA (0.40) FDPSGAAGGPS1
SCHEMBL7636622 0.70 GAA (0.43) FDPSGAA
SCHEMBL12776907 0.70 GAA (0.43) FDPSGAA
SCHEMBL8299065 0.69 FDPS (0.37) FDPSGAAGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421225-B2 Heteroaromatic amide derivative and medicament containing the same KAKEN PHARMACEUTICAL CO., LTD. (JP) 2025-09-23 US disclosed
CN-114929779-B Method for producing aliphatic aromatic polyester 三菱化学株式会社 2025-05-02 CN disclosed
EP-3851436-B1 NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME KAKEN PHARMA CO LTD (JP) 2024-06-12 EP disclosed
WO-2023149675-A1 POLYESTER RESIN COMPOSITION FOR FILM CONTAINING TITANIUM-BASED CATALYST AND PREPARATION METHOD THEREFOR 도레이첨단소재 주식회사 2023-08-10 WO disclosed
CN-116406231-A Molecules having certain pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2023-07-07 CN disclosed
US-20230086366-A1 Novel heteroaromatic amide derivative and medicament containing the same KAKEN PHARMACEUTICAL CO., LTD. (JP) 2023-03-23 US disclosed
US-11472891-B2 Photocrosslinkable alginic acid derivative MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-10-18 US disclosed
US-20210380727-A1 NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2021-12-09 US disclosed
EP-3851436-A1 NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME Kaken Pharmaceutical Co., Ltd. (JP) 2021-07-21 EP disclosed
US-10898469-B2 Imidazolylamide derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2021-01-26 US disclosed
EP-0677524-A1 Thieno[3,2-F][1,2,4]triazolo[4,3-A][1,4]diazepine derivatives as PAF antagonists Eisai Co., Ltd. (JP) 1995-10-18 EP disclosed
US-5438045-A An 3-acetyl-6-phenyl-2,3,4,5-tetrahydro-8h-pyrido(4'3':4,5)-thieno(3,2 -f)(1,2,4)triazolo(4,3-a)(1,4)diazepine derivative; antiallergens; asthma; antiplatelet activating factor activity EISAI CO., LTD. (JP) 1995-08-01 US disclosed
US-5409909-A Antiallergens EISAI CO., LTD. (JP) 1995-04-25 US disclosed
US-5382579-A Platelet activating factor antagonists; antiallergens; asthma EISAI CO., LTD. (JP) 1995-01-17 US disclosed
EP-0350958-B1 Improved polyimide and polyimide film and manufacturing method thereof KANEGAFUCHI CHEMICAL IND (JP) 1994-12-21 EP disclosed
EP-0606103-A1 Thieno 3.2-f 1,2,4 triazolo 4,3-a 1,4 -diazepine derivatives as PAF antagonists Eisai Co., Ltd. (JP) 1994-07-13 EP disclosed
US-5304553-A Antiallergens; platelet activating factor inhibitor EISAI CO., LTD. (JP) 1994-04-19 US disclosed
US-5221671-A Antiallergens, bronchodilator agents EISAI CO., LTD. (JP) 1993-06-22 US disclosed
EP-0367110-A1 1,4-diazepine derivative and its pharmaceutical use Eisai Co., Ltd. (JP) 1990-05-09 EP disclosed
EP-0350958-A2 Improved polyimide and polyimide film and manufacturing method thereof KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230086366-A1 Novel heteroaromatic amide derivative and medicament containing the same SCN7A, HCN4, SCN4A FDPS 4800/4885GAA 3381/4885GGPS1 4873/4885
US-12421225-B2 Heteroaromatic amide derivative and medicament containing the same SCN7A, HCN4, SCN4A FDPS 4811/4885GAA 3549/4885GGPS1 4879/4885
US-10898469-B2 Imidazolylamide derivative NR4A3, NR3C2, NR4A2 FDPS 3898/4885GAA 4802/4885GGPS1 4196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.