Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373989 | 1.00 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL8377780 | 1.00 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL9694226 | 0.85 | LMNA (0.36) | LMNAL3MBTL1TDP1 | |
| SCHEMBL6139270 | 0.85 | LMNA (0.36) | LMNAL3MBTL1TDP1 | |
| SCHEMBL27610347 | 0.84 | LMNA (0.43) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL18285214 | 0.76 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL9501106 | 0.75 | LMNA (0.50) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL9748371 | 0.75 | LMNA (0.50) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL9326932 | 0.75 | LMNA (0.50) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL8718053 | 0.73 | LMNA (0.48) | LMNAL3MBTL1TDP1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173161-A2 | GLUCAMINE COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 2002-01-23 | — | — | EP | disclosed |
| CN-1290168-A | Inhibition of membrane-associated viral replication | UNIV OXFORD (GB) | 2001-04-04 | — | — | CN | disclosed |
| WO-2001008672-A2 | GLUCAMINE COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 2001-02-08 | — | — | WO | disclosed |