Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 8/20 | 0.54 |
| ▸ | RXRB | P28702 | 8/20 | 0.54 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | RXRG | P48443 | 5/20 | 0.42 |
| ▸ | RARA | P10276 | 3/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608030 | 0.84 | RXRA (0.75) | RXRACYP26A1RXRBCYP26B1CYP3A4 | |
| SCHEMBL8702754 | 0.82 | RXRA (0.76) | RXRACYP26A1RXRBCYP26B1CYP3A4 | |
| SCHEMBL7458443 | 0.82 | RXRA (0.61) | RXRACYP26A1RXRBCYP26B1CYP3A4 | |
| SCHEMBL8707418 | 0.76 | RXRA (0.72) | RXRACYP26A1RXRBCYP26B1CYP3A4 | |
| SCHEMBL2788640 | 0.74 | CYP3A4 (0.70) | RXRACYP26A1RXRBCYP26B1CYP3A4 | |
| SCHEMBL8708782 | 0.73 | RXRA (0.74) | RXRACYP26A1RXRBCYP26B1CYP3A4 | |
| SCHEMBL8706548 | 0.72 | RXRA (0.78) | RXRACYP26A1RXRBCYP26B1CYP3A4 | |
| SCHEMBL7421190 | 0.72 | RXRA (0.72) | RXRACYP26A1RXRBCYP26B1CYP3A4 | |
| SCHEMBL9319204 | 0.72 | CYP3A4 (0.67) | RXRACYP26A1RXRBCYP26B1CYP3A4 | |
| SCHEMBL3794870 | 0.72 | RXRA (0.43) | RXRACYP26A1RXRBCYP26B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003493-A4 | USE OF SELECTIVE RXR AGONISTS TO PREVENT SURGICAL ADHESIONS | BRISTOL MYERS SQUIBB CO (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1003493-A1 | USE OF SELECTIVE RXR AGONISTS TO PREVENT SURGICAL ADHESIONS | Bristol-Myers Squibb Company (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999006036-A1 | USE OF SELECTIVE RXR AGONISTS TO PREVENT SURGICAL ADHESIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |