Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.41 |
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 3/20 | 0.40 |
| ▸ | CLK2 | P49760 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5125618 | 0.97 | MAPT (0.50) | MAPTNPSR1PDE5AMEN1KMT2A | |
| SCHEMBL7515049 | 0.92 | BCDIN3D (0.41) | MAPTNPSR1PDE5ATSHRKDM4E | |
| SCHEMBL5114975 | 0.91 | MAPT (0.44) | MAPTNPSR1PDE5AMEN1KMT2A | |
| SCHEMBL5122882 | 0.88 | BCDIN3D (0.41) | MAPTNPSR1PDE5AMEN1KMT2A | |
| SCHEMBL7504877 | 0.87 | MAPT (0.41) | MAPTNPSR1PDE5AMEN1KMT2A | |
| SCHEMBL7522686 | 0.86 | MAPT (0.65) | MAPTNPSR1PDE5AMEN1KMT2A | |
| SCHEMBL5122159 | 0.86 | MAPT (0.50) | MAPTNPSR1PDE5AMEN1KMT2A | |
| SCHEMBL5121879 | 0.86 | MAPT (0.50) | MAPTNPSR1PDE5AMEN1KMT2A | |
| SCHEMBL5116032 | 0.85 | USP1 (0.50) | MAPTNPSR1PDE5AMEN1KMT2A | |
| SCHEMBL5117960 | 0.84 | USP1 (0.49) | MAPTNPSR1PDE5AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998006722-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |