Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752966 | 0.70 | ALDH1A1 (0.34) | ALDH1A1POLBLMNATSHRCNR2 | |
| SCHEMBL3221601 | 0.68 | HTT (0.47) | ALDH1A1POLBLMNAUSP2NPSR1 | |
| SCHEMBL752032 | 0.68 | ALDH1A1 (0.41) | ALDH1A1POLBLMNATSHRNPSR1 | |
| SCHEMBL752052 | 0.67 | POLB (0.39) | ALDH1A1POLBLMNATSHRCNR2 | |
| SCHEMBL3222142 | 0.67 | TDP1 (0.58) | POLBHTTMAPTNPC1RAB9A | |
| SCHEMBL4677316 | 0.67 | HTT (0.44) | ALDH1A1POLBLMNATSHRUSP2 | |
| SCHEMBL755129 | 0.66 | ALDH1A1 (0.34) | ALDH1A1POLBLMNATSHRCNR2 | |
| SCHEMBL3218824 | 0.66 | HTT (0.43) | ALDH1A1POLBLMNATSHRUSP2 | |
| Bromide SCHEMBL4677319 | 0.66 | TDP1 (0.56) | POLBHTTMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL755891 | 0.66 | TDP1 (0.56) | POLBHTTMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |