Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520343 | 1.00 | MAOB (0.46) | MAOBAHRCYP1A2NFE2L2DAO | |
| SCHEMBL7518821 | 0.83 | PTGS1 (0.39) | MAOBMAOANPC1RAB9A | |
| SCHEMBL7520656 | 0.83 | PTGS1 (0.39) | MAOBMAOANPC1RAB9A | |
| SCHEMBL7518829 | 0.83 | PTGS1 (0.39) | MAOBMAOANPC1RAB9A | |
| SCHEMBL7523379 | 0.82 | MAOB (0.42) | MAOBCYP1A2NFE2L2MAOANPC1 | |
| SCHEMBL7523377 | 0.82 | MAOB (0.42) | MAOBCYP1A2NFE2L2MAOANPC1 | |
| SCHEMBL7519323 | 0.80 | AHR (0.47) | AHRCYP1A2NFE2L2FBP1 | |
| SCHEMBL7515524 | 0.80 | AHR (0.47) | AHRCYP1A2NFE2L2FBP1 | |
| SCHEMBL7515044 | 0.79 | SMN1; SMN2 (0.48) | AHRCYP1A2NFE2L2HSD17B10NPC1 | |
| SCHEMBL7515036 | 0.79 | SMN1; SMN2 (0.48) | AHRCYP1A2NFE2L2HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |