Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518821 | 1.00 | PTGS1 (0.39) | PTGS1PTGS2APPRAB9AKDM4E | |
| SCHEMBL7518829 | 1.00 | PTGS1 (0.39) | PTGS1PTGS2APPRAB9AKDM4E | |
| SCHEMBL7520340 | 0.83 | MAOB (0.46) | RAB9AMAOBMAOANPC1 | |
| SCHEMBL7520343 | 0.83 | MAOB (0.46) | RAB9AMAOBMAOANPC1 | |
| SCHEMBL7523379 | 0.82 | MAOB (0.42) | RAB9AKDM4EALDH1A1HPGDCYP2C19 | |
| SCHEMBL7523377 | 0.82 | MAOB (0.42) | RAB9AKDM4EALDH1A1HPGDCYP2C19 | |
| SCHEMBL7515524 | 0.80 | AHR (0.47) | PTGS1PTGS2PIM1PIM2 | |
| SCHEMBL7519323 | 0.80 | AHR (0.47) | PTGS1PTGS2PIM1PIM2 | |
| SCHEMBL7515036 | 0.79 | SMN1; SMN2 (0.48) | PTGS1PTGS2RAB9AKDM4EALDH1A1 | |
| SCHEMBL7515044 | 0.79 | SMN1; SMN2 (0.48) | PTGS1PTGS2RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |