Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519068 | 1.00 | GPR119 (0.49) | GPR119IDO1TDO2ALOX5APFEN1 | |
| SCHEMBL7526229 | 0.89 | GPR119 (0.51) | GPR119IDO1TDO2ALOX5APFEN1 | |
| SCHEMBL7513981 | 0.89 | GPR119 (0.50) | GPR119ALOX5APFEN1CHEK2STS | |
| SCHEMBL7524187 | 0.87 | GPR119 (0.49) | GPR119IDO1TDO2ALOX5APFEN1 | |
| SCHEMBL7513551 | 0.87 | GPR119 (0.49) | GPR119IDO1TDO2ALOX5APFEN1 | |
| SCHEMBL7524540 | 0.85 | GPR119 (0.48) | GPR119IDO1TDO2ALOX5APFEN1 | |
| SCHEMBL7523559 | 0.85 | GPR119 (0.48) | GPR119IDO1TDO2ALOX5APFEN1 | |
| SCHEMBL7468249 | 0.85 | GPR119 (0.48) | GPR119IDO1TDO2ALOX5APFEN1 | |
| SCHEMBL7518505 | 0.83 | GPR119 (0.47) | GPR119IDO1TDO2ALOX5APFEN1 | |
| SCHEMBL7515633 | 0.83 | GPR119 (0.46) | GPR119IDO1TDO2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | LIN NAN-HORNG (US) | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | GAP43, SLC18A2, GABRE | GPR119 604/4885IDO1 4137/4885TDO2 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.