Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 9/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522216 | 0.86 | PARP1 (0.50) | ALDH1A1PTGDR2HPGDKDM4ETDP1 | |
| SCHEMBL10591734 | 0.85 | MAPT (0.49) | LTB4RLTB4R2MAPTALDH1A1RAB9A | |
| SCHEMBL6836494 | 0.81 | MAOB (0.55) | MAPTALDH1A1RAB9AHPGDTDP1 | |
| SCHEMBL7383487 | 0.77 | ABCB1 (0.52) | ALDH1A1PTGDR2HPGDKDM4ETDP1 | |
| SCHEMBL768807 | 0.76 | MAPT (0.55) | MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL7972637 | 0.76 | LTB4R (0.43) | LTB4RLTB4R2MAPTALDH1A1RAB9A | |
| SCHEMBL7525144 | 0.75 | PTGDR2 (0.40) | ALDH1A1PTGDR2HPGDKDM4ETDP1 | |
| SCHEMBL9124055 | 0.75 | LTB4R (0.78) | LTB4RLTB4R2 | |
| SCHEMBL28550871 | 0.74 | MRGPRX4 (0.60) | LTB4RLTB4R2ALDH1A1PTGDR2HPGD | |
| SCHEMBL1839684 | 0.74 | MRGPRX4 (0.63) | LTB4RLTB4R2ALDH1A1PTGDR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417213-B2 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-09 | — | — | US | disclosed |
| US-20020006944-A1 | Tricyclic compounds, their production and use | OHKAWA SHIGENORI (JP) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006944-A1 | Tricyclic compounds, their production and use | CNR1, PTGER1, PTGDR | LTB4R 25/4885LTB4R2 29/4885MAPT 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.