Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38657670 | 0.89 | SLC7A5 (0.53) | PTGS2ALPIPKMPTGS1XIAP | |
| SCHEMBL6956712 | 0.81 | PTGS2 (0.44) | LTA4HKIF11ALDH1A1PTGS2PTPN1 | |
| SCHEMBL13849496 | 0.81 | PTGS2 (0.44) | LTA4HKIF11ALDH1A1PTGS2PTPN1 | |
| Hydrochloric Acid SCHEMBL2292315 | 0.79 | PPARG (0.54) | LTA4HALDH1A1PTGS2ALPIPKM | |
| Hydrochloric Acid SCHEMBL2292318 | 0.79 | PPARG (0.54) | LTA4HALDH1A1PTGS2ALPIPKM | |
| Phenylalanine Methyl Ester SCHEMBL136408 | 0.79 | SLC7A5 (0.61) | LTA4HALDH1A1MEN1KMT2AALPI | |
| Phenylalanine Methyl Ester SCHEMBL136409 | 0.79 | SLC7A5 (0.61) | LTA4HALDH1A1MEN1KMT2AALPI | |
| Phenylalanine Methyl Ester SCHEMBL7738570 | 0.79 | SLC7A5 (0.61) | LTA4HALDH1A1MEN1KMT2AALPI | |
| Phenylalanine Methyl Ester SCHEMBL346467 | 0.79 | SLC7A5 (0.61) | LTA4HALDH1A1MEN1KMT2AALPI | |
| Phenylalanine Methyl Ester SCHEMBL27544207 | 0.79 | SLC7A5 (0.61) | LTA4HALDH1A1MEN1KMT2AALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973945-A4 | CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING SAME | ISIS PHARMACEUTICALS INC (US) | 2002-07-17 | — | — | EP | disclosed |
| EP-0973945-A1 | CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING SAME | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-26 | — | — | EP | disclosed |
| US-6015887-A | PREPARING SYNTHETIC MONOMERS BY DEHYDRATIVE COUPLING OF AMINE AND ALCOHOL STARTING REAGENTS | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-18 | — | — | US | disclosed |
| WO-1998046794-A1 | CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING SAME | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |