Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466969 | 0.92 | FFAR4 (0.39) | CETPFFAR4UBE2MDCUN1D1LMNA | |
| SCHEMBL512504 | 0.86 | CETP (0.38) | CETPFFAR4UBE2MDCUN1D1LMNA | |
| SCHEMBL512503 | 0.83 | FFAR4 (0.37) | CETPFFAR4UBE2MDCUN1D1LMNA | |
| SCHEMBL12300586 | 0.80 | CETP (0.41) | CETPFFAR4UBE2MDCUN1D1PTPRZ1 | |
| SCHEMBL13064250 | 0.77 | CETP (0.40) | CETPFFAR4UBE2MDCUN1D1PTPRZ1 | |
| SCHEMBL3278395 | 0.76 | CETP (0.42) | CETPFFAR4UBE2MDCUN1D1LMNA | |
| SCHEMBL3544087 | 0.76 | FFAR4 (0.45) | CETPFFAR4UBE2MDCUN1D1LMNA | |
| SCHEMBL7527885 | 0.76 | LMNA (0.55) | LMNAGAAMAPTKDM4EALDH1A1 | |
| SCHEMBL513845 | 0.73 | PTPRZ1 (0.39) | CETPFFAR4UBE2MDCUN1D1LMNA | |
| SCHEMBL513846 | 0.73 | PTPRZ1 (0.42) | CETPFFAR4UBE2MDCUN1D1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015609-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |