Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10857657 | 0.78 | KDM4E (0.36) | — | |
| SCHEMBL7145732 | 0.75 | — | — | |
| SCHEMBL434032 | 0.74 | KDM4E (0.32) | — | |
| SCHEMBL5062914 | 0.70 | KDM4E (0.32) | — | |
| SCHEMBL8826213 | 0.70 | TDP1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL21174542 | 0.69 | KDM4E (0.32) | — | |
| Butane SCHEMBL10551688 | 0.69 | CYP1A2 (0.36) | — | |
| 2-Aminopurine SCHEMBL10551243 | 0.68 | ALDH1A1 (0.42) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11066168 | 0.68 | PDK2 (0.35) | — | |
| SCHEMBL375954 | 0.67 | PDK2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000053603-A9 | 2-HYDROXY METHYLCYCLOPRO PYLIDENEMETHYL PURINES AND -PYRIMIDINES AS ANTIVIRAL AGENTS | UNIV MICHIGAN (US) | 2002-05-10 | — | — | WO | disclosed |
| EP-1165560-A4 | 2-HYDROXY METHYLCYCLOPRO PYLIDENEMETHYL PURINES AND -PYRIMIDINES AS ANTIVIRAL AGENTS | UNIV MICHIGAN (US) | 2002-04-17 | — | — | EP | disclosed |
| EP-1165560-A1 | 2-HYDROXY METHYLCYCLOPRO PYLIDENEMETHYL PURINES AND -PYRIMIDINES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000053603-A1 | 2-HYDROXY METHYLCYCLOPRO PYLIDENEMETHYL PURINES AND -PYRIMIDINES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2000-09-14 | — | — | WO | disclosed |