Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.70 |
| ▸ | LTA4H | P09960 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 7/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975634 | 0.99 | EBP (0.72) | EBPSIGMAR1LTA4HESR1ESR2 | |
| SCHEMBL7524285 | 0.94 | EBP (0.65) | EBPSIGMAR1LTA4HESR1ESR2 | |
| SCHEMBL13897766 | 0.94 | EBP (0.65) | EBPSIGMAR1LTA4HESR1ESR2 | |
| SCHEMBL7109994 | 0.94 | EBP (0.61) | EBPSIGMAR1LTA4HESR1ESR2 | |
| SCHEMBL13897747 | 0.94 | EBP (0.66) | EBPSIGMAR1LTA4HESR1ESR2 | |
| SCHEMBL7105837 | 0.93 | EBP (0.62) | EBPSIGMAR1LTA4HESR1ESR2 | |
| SCHEMBL7108683 | 0.91 | EBP (0.59) | EBPSIGMAR1LTA4HESR1ESR2 | |
| SCHEMBL3869661 | 0.90 | EBP (0.58) | EBPSIGMAR1ESR1ESR2HRH3 | |
| SCHEMBL7110875 | 0.89 | EBP (0.58) | EBPSIGMAR1LTA4HESR1ESR2 | |
| SCHEMBL7109917 | 0.89 | EBP (0.56) | EBPSIGMAR1LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501441-B1 | Naphthyl compounds, intermediates, processes, compositions, and methods | ELI LILLY AND COMPANY (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501441-B1 | Naphthyl compounds, intermediates, processes, compositions, and methods | ELI LILLY AND COMPANY (US) | 2009-03-10 | — | — | US | disclosed |
| EP-0703228-B1 | Naphthyl compounds, intermediates, processes, compositions involving them | LILLY CO ELI (US) | 2002-03-06 | — | — | EP | disclosed |