Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10596261 | 0.87 | APP (0.50) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL3795027 | 0.87 | PTGS1 (0.45) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL4267538 | 0.84 | EPHX2 (0.49) | EPHX2 | |
| SCHEMBL16445681 | 0.84 | EPHX2 (0.49) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL8755997 | 0.83 | APP (0.37) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL28065626 | 0.83 | APP (0.42) | APPEPHX2PTGS1PDE4ALMNA | |
| SCHEMBL4273656 | 0.82 | EPHX2 (0.51) | EPHX2 | |
| SCHEMBL9390890 | 0.82 | EPHX2 (0.51) | EPHX2 | |
| SCHEMBL10695345 | 0.82 | EPHX2 (0.60) | EPHX2 | |
| SCHEMBL14243982 | 0.82 | EPHX2 (0.51) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176987-A2 | SHORT-CHAIN PEPTIDE DYE CONJUGATES USED AS CONTRAST AGENTS FOR OPTICAL DIAGNOSTICS | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000061194-A2 | SHORT-CHAIN PEPTIDE DYE CONJUGATES USED AS CONTRAST AGENTS FOR OPTICAL DIAGNOSTICS | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 2000-10-19 | — | — | WO | disclosed |
| US-5082759-A | Liquid developer for electrostatic photography | FUJI PHOTO FILM CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0465939-A1 | Double reactive dyestuffs with four halogenetriazinyl anchors | BASF Aktiengesellschaft (DE) | 1992-01-15 | — | — | EP | disclosed |