Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16143805 | 0.90 | APP (0.42) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL16446001 | 0.88 | EPHX2 (0.42) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL8942933 | 0.87 | APP (0.44) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL7521234 | 0.87 | APP (0.44) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL11061814 | 0.86 | EPHX2 (0.53) | APPEPHX2 | |
| SCHEMBL9683215 | 0.85 | APP (0.42) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL7026742 | 0.84 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL21485088 | 0.84 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL28382453 | 0.84 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL798530 | 0.82 | APP (0.37) | APPPTGS1PDE4ALMNASLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874684-A | FOR MULTICOLOR SYSTEMS GIVING IMAGES OF SAME HUE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-17 | — | — | US | disclosed |
| US-4770870-A | BY ALSO ADMINISTERING A THIO COMPOUND, I.E. CYSTEINE; ANTICANCER AGENT | ASTA PHARMA AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |
| US-4057430-A | MEROCYANINE THIOHYDANTOIN SENSITIZERS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-11-08 | — | — | US | disclosed |