Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862331 | 0.92 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP3A4NPC1RAB9APIN1 | |
| SCHEMBL7655370 | 0.91 | NPC1 (0.36) | SMN1; SMN2NPC1RAB9APIN1TP53 | |
| SCHEMBL7516817 | 0.86 | HTT (0.45) | SMN1; SMN2CYP3A4NPC1RAB9ATP53 | |
| SCHEMBL7521872 | 0.85 | HPGD (0.46) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL7519989 | 0.83 | NPC1 (0.45) | SMN1; SMN2CYP3A4NPC1RAB9AMAPT | |
| SCHEMBL6861261 | 0.82 | NPC1 (0.36) | SMN1; SMN2NPC1RAB9APIN1TP53 | |
| SCHEMBL11136454 | 0.81 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL29708 | 0.78 | NPC1 (0.49) | SMN1; SMN2CYP3A4NPC1RAB9APOLB | |
| SCHEMBL29350736 | 0.78 | NPC1 (0.49) | SMN1; SMN2CYP3A4NPC1RAB9APOLB | |
| SCHEMBL6860452 | 0.78 | HPGD (0.47) | SMN1; SMN2NPC1RAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489383-B1 | SUCH AS 2-(2-HYDROXY-3-(1,1-DI(4-2-(BROMOETHOXY)PHENYL) ETHYL)-5-TERT-BUTYLPHENYL)-2H-BENZOTRIAZOLE FOR USE AS STOVING LACQUER, FINISHING ENAMEL FOR AUTOMOBILES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-12-03 | — | — | US | disclosed |
| US-20020169239-A1 | 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith | WOOD MERVIN G (US) | 2002-11-14 | — | — | US | disclosed |
| US-6392056-B1 | FOR THERMOPLASTIC RESINS | CIBA SPECIALTY CHEMICAL CORPORATION | 2002-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169239-A1 | 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith | SUV39H1, SUV39H2, PAH | SMN1; SMN2 3397/4885CYP3A4 72/4885NPC1 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.