Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA3 | P07451 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA5A | P35218 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.65 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.65 |
| ▸ | FNTA | P49354 | 1/20 | 0.57 |
| ▸ | FNTB | P49356 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521630 | 1.00 | ANPEP (0.69) | ANPEPCA12CA1CA2CA3 | |
| SCHEMBL9821905 | 0.91 | ANPEP (0.65) | ANPEPCA12CA1CA2CA3 | |
| SCHEMBL24301278 | 0.87 | ANPEP (0.54) | ANPEPCA12CA1CA2CA3 | |
| SCHEMBL6236631 | 0.86 | ANPEP (0.61) | ANPEPCA12CA1CA2CA3 | |
| SCHEMBL22905316 | 0.85 | CA1 (0.70) | ANPEPCA12CA1CA2CA3 | |
| SCHEMBL1895974 | 0.85 | CA1 (0.70) | ANPEPCA12CA1CA2CA3 | |
| SCHEMBL9366412 | 0.83 | ANPEP (0.56) | ANPEPCA12CA1CA2CA3 | |
| SCHEMBL31291804 | 0.83 | CTSK (0.65) | ANPEPCA2CTSSCTSK | |
| SCHEMBL8836882 | 0.82 | GNPAT (0.61) | ANPEPFNTAFNTB | |
| SCHEMBL47275 | 0.81 | CA12 (0.74) | ANPEPCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194464-B1 | AMINO ACID DERIVATIVES AND USE THEREOF FOR THE PREPARATION OF AN ANTICONVULSANT | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1991-04-03 | — | — | EP | claimed |
| EP-0194464-A1 | Amino acid derivatives and use thereof for the preparation of an anticonvulsant | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1986-09-17 | — | — | EP | claimed |
| EP-0400440-B1 | Amino acid derivative anticonvulsant | RES CORP TECHNOLOGIES INC (US) | 2002-03-13 | — | — | EP | disclosed |
| US-5654301-A | Lacosamide FDA Orange book listed patent | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5378729-A | Diamide derivatives | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0592490-A4 | AMINO ACID DERIVATIVE ANTICONVULSANT | RES CORP TECHNOLOGIES INC (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0592490-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0263506-B1 | ANTICONVULSANT COMPOSITION CONTAINING AMINO ACID DERIVATIVE AND USE OF SAID AMINO ACID DERIVATIVE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| WO-1992021648-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-10 | — | — | WO | disclosed |
| EP-0194464-B1 | AMINO ACID DERIVATIVES AND USE THEREOF FOR THE PREPARATION OF AN ANTICONVULSANT | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1991-04-03 | — | — | EP | disclosed |
| WO-1990015069-A2 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-13 | — | — | WO | disclosed |
| EP-0400440-A1 | Amino acid derivative anticonvulsant | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0263506-A2 | Anticonvulsant composition containing amino acid derivative and use of said amino acid derivative | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0194464-A1 | Amino acid derivatives and use thereof for the preparation of an anticonvulsant | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1986-09-17 | — | — | EP | disclosed |