SCHEMBL7521709

SCHEMBL7521709

CC(=O)c1ccc(-c2ccc(C(C)=O)cc2-c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
S100A4 P26447 1/20 0.56
HSD17B1 P14061 2/20 0.53
PTGS2 P35354 1/20 0.52
SGK1 O00141 1/20 0.49
SYK P43405 1/20 0.49
AURKB Q96GD4 1/20 0.49
INCENP Q9NQS7 1/20 0.49
LMNA P02545 2/20 0.47
EGFR P00533 1/20 0.47
HPGD P15428 3/20 0.47
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KMT2A Q03164 2/20 0.46
CHEK1 O14757 1/20 0.46
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
TAAR1 Q96RJ0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14176467 0.96 MAPT (0.61) MAPTSMN1; SMN2S100A4HSD17B1PTGS2
SCHEMBL10296041 0.88 MAPT (0.79) MAPTSMN1; SMN2S100A4HSD17B1PTGS2
Hydrogen Sulfide SCHEMBL28788713 0.86 MAPT (0.76) MAPTSMN1; SMN2S100A4HSD17B1PTGS2
Fluoride SCHEMBL27907086 0.85 MAPT (0.73) MAPTSMN1; SMN2S100A4HSD17B1PTGS2
SCHEMBL11448863 0.84 MAPT (0.71) MAPTSMN1; SMN2S100A4HSD17B1SGK1
SCHEMBL13232064 0.82 MAPT (0.63) MAPTSMN1; SMN2S100A4HSD17B1SGK1
SCHEMBL12332689 0.82 MAPT (0.68) MAPTSMN1; SMN2S100A4HSD17B1SGK1
SCHEMBL7252924 0.82 MAPT (1.00) MAPTSMN1; SMN2HSD17B1LMNAHPGD
SCHEMBL7738989 0.82 MAPT (1.00) MAPTSMN1; SMN2HSD17B1LMNAHPGD
SCHEMBL51207 0.82 MAPT (1.00) MAPTSMN1; SMN2HSD17B1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119926191-B Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof 中山大学 2025-06-13 CN disclosed
CN-119926191-A Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof 中山大学 2025-05-06 CN disclosed
WO-2017015693-A1 LUMINESCENT BIOMOLECULAR COMPLEX AND USE THEREOF MACQUARIE UNIVERSITY (AU) 2017-02-02 WO disclosed
US-6455684-B1 FLUORESCENT COMPLEX OF A PROBE AND A HEAVY METAL ION SUCH AS LANTHANIDE SERIES ION, WHERE THE PROBE INCLUDES PERFLUOROALKYL BETA-DIKETONATO GROUP(S); HIGH PRECISION AND HIGH SENSITIVITY Matsumoto, Kazuko (JP) 2002-09-24 US disclosed
US-20020106674-A1 In situ assay of substance in biological sample using labeled probe TOYO BOSEKI KABUSHIKI KAISHA (JP) 2002-08-08 US disclosed
US-6339172-B1 REACTING LABELED NUCLEIC ACID PROBE WITH AN OBJECTIVE SUBSTANCE ON A BIOLOGICAL SAMPLE SELECTED FROM TISSUE, CELL AND CHROMOSOME ADDING HEAVY METAL AND ASSAYING FLUORESCENCE OF COMPLEX FORMED Matsumoto, Kazuko (JP) 2002-01-15 US disclosed
US-6166251-A Labeled reagents for use in immunoassays and fluorescent compounds and complexes used therein KAZUKO MATSUMOTO (JP) 2000-12-26 US disclosed
EP-0794174-B1 Labeled reagents for use in immunoassays and fluorescent compounds and complexes used therein SUZUKI MOTOR CO (JP) 2000-06-14 EP disclosed
US-5859297-A A BETA-DIKETONE HAVING ONE OR MORE AROMATIC RING GROUPS IN CONJUGATED CONFIGURATION, AND ELECTRON-ATTRACTING FLUORINE-SUBSTITUTED ALKYL GROUPS; LESS MEASURING STEPS, HIGH EMISSION INTENSITIES, SOLID AND LIQUID PHASE MEASUREMENTS Matsumoto, Kazuko (JP) 1999-01-12 US disclosed
EP-0794174-A2 Labeled reagents for use in immunoassays and fluorescent compounds and complexes used therein SUZUKI MOTOR CORPORATION (JP) 1997-09-10 EP disclosed