SCHEMBL7521875

SCHEMBL7521875

CCNC1CCC1.CO[SiH2]OC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.38
ALDH1A1 P00352 5/20 0.34
TSHR P16473 1/20 0.34
KDM4E B2RXH2 5/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ROCK1 Q13464 1/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL454473 0.83
Hydrochloric Acid SCHEMBL15848302 0.81
SCHEMBL19171960 0.79 KDM4E (0.38) ALDH1A1TSHRKDM4ECYP1A2CYP2D6
SCHEMBL465770 0.78
SCHEMBL26455030 0.77 KCNH2 (0.36) KCNH2ALDH1A1TSHRKDM4ECYP1A2
SCHEMBL22416728 0.76 KDM4E (0.48) KCNH2ALDH1A1KDM4ECYP1A2CYP2D6
SCHEMBL22790769 0.76 KDM4E (0.48) KCNH2ALDH1A1KDM4ECYP1A2CYP2D6
SCHEMBL22316957 0.76 KDM4E (0.48) KCNH2ALDH1A1KDM4ECYP1A2CYP2D6
Hydrochloric Acid SCHEMBL1915912 0.76
SCHEMBL24728 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0866734-B1 METHOD AND COMPOSITION USEFUL FOR TREATING METAL SURFACES CHEMAT TECHNOLOGY INC (US) 2002-03-06 EP claimed