Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 4/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524253 | 0.82 | MME (0.40) | ALDH1A1EEF2KL3MBTL1FFAR1MEN1 | |
| SCHEMBL7520247 | 0.81 | ALDH1A1 (0.39) | ALDH1A1EEF2KMRGPRX4FFAR1CTSA | |
| SCHEMBL7528945 | 0.79 | FFAR1 (0.47) | EEF2KFFAR1CTSA | |
| SCHEMBL31750382 | 0.78 | ALDH1A1 (0.44) | ALDH1A1EEF2KMRGPRX4L3MBTL1FFAR1 | |
| SCHEMBL7517891 | 0.77 | CACNA2D1 (0.46) | ALDH1A1L3MBTL1FFAR1MEN1KMT2A | |
| SCHEMBL7522886 | 0.73 | MEN1 (0.47) | ALDH1A1MEN1KMT2ACTSA | |
| SCHEMBL7522036 | 0.73 | EEF2K (0.44) | EEF2KFFAR1CTSA | |
| SCHEMBL7522581 | 0.72 | ALDH1A1 (0.43) | ALDH1A1FFAR1 | |
| SCHEMBL7519215 | 0.71 | AKR1B1 (0.42) | ALDH1A1KMT2ACTSA | |
| SCHEMBL16829661 | 0.71 | PDE2A (0.50) | ALDH1A1MRGPRX4L3MBTL1FFAR1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181267-A1 | HALOGEN COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000071500-A1 | HALOGEN COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-30 | — | — | WO | disclosed |