Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521992 | 0.91 | AR (0.36) | ESR1 | |
| SCHEMBL7517269 | 0.87 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL7526690 | 0.80 | MEN1 (0.36) | ESR1ESR2 | |
| SCHEMBL7520384 | 0.79 | — | — | |
| SCHEMBL7517845 | 0.75 | — | — | |
| SCHEMBL7526589 | 0.75 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL7517206 | 0.75 | AR (0.37) | ESR1ESR2 | |
| SCHEMBL7522333 | 0.73 | MEN1 (0.38) | ESR1ESR2 | |
| SCHEMBL7515139 | 0.71 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL7520619 | 0.71 | MEN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |