SCHEMBL752261

SCHEMBL752261

N#CC1CC(C(=O)O)N(C(=O)O)C1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22029860 1.00 ATM (0.39) ATM
SCHEMBL31037771 1.00 ATM (0.39) ATM
SCHEMBL21196005 1.00 ATM (0.39) ATM
SCHEMBL6592886 1.00 ATM (0.39) ATM
SCHEMBL19083751 0.85 ATM (0.58) ATM
SCHEMBL12491603 0.81 MMP2 (0.44)
SCHEMBL19075597 0.81 ATM (0.38) ATM
SCHEMBL23730559 0.77 HSD17B10 (0.39) ATM
SCHEMBL2708021 0.77 HSD17B10 (0.39) ATM
SCHEMBL1269658 0.77 HSD17B10 (0.39) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658667-A1 CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY Merck Sharp & Dohme LLC (US) 2025-12-10 EP disclosed
WO-2024163691-A1 CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY MERCK SHARP & DOHME LLC (US) 2024-08-08 WO disclosed
EP-4143162-A1 ALKYLAMINOPROLINE DERIVATIVES AS ALFA-2-DELTA-1 BLOCKERS Acondicionamiento Tarrasense (ES) 2023-03-08 EP disclosed
CN-109020961-A Antiviral compound 吉利德制药有限责任公司 2018-12-18 CN disclosed
CN-104230900-B Antiviral compound 吉利德制药有限责任公司 2018-10-19 CN disclosed
CN-106588890-A Antiviral compounds 吉利德制药有限责任公司 2017-04-26 CN disclosed
CN-104211713-B Antiviral compounds 吉利德制药有限责任公司 2017-04-12 CN disclosed
CN-104211689-B Antiviral compounds 吉利德制药有限责任公司 2017-01-18 CN disclosed
CN-103977406-B Antiviral compound 吉利德制药有限责任公司 2016-10-19 CN disclosed
EP-2430014-A1 ANTIVIRAL COMPOUNDS Gilead Sciences, Inc. (US) 2012-03-21 EP disclosed
WO-2010132601-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2010-11-18 WO disclosed