Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.80 |
| ▸ | RAB9A | P51151 | 8/20 | 0.80 |
| ▸ | MEN1 | O00255 | 6/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | CASP2 | P42575 | 1/20 | 0.63 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19392293 | 0.95 | NPC1 (0.89) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL1929165 | 0.90 | NPC1 (0.85) | NPC1RAB9AMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL31228835 | 0.88 | NPC1 (0.82) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL11887623 | 0.87 | MEN1 (1.00) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL29684351 | 0.86 | KCNK3 (0.74) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL8771200 | 0.84 | NPC1 (0.89) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL12259170 | 0.84 | KCNK3 (0.84) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11729204 | 0.83 | MEN1 (0.80) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL2063276 | 0.83 | NPC1 (0.86) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL15434968 | 0.83 | LMNA (0.74) | NPC1RAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021160-B1 | CARBOXYMIDE AND ANILINE DERIVATIVES AS SELECTIVE INHIBITORS OF PATHOGENS | AXXIMA PHARMACEUTICALS AG (DE) | 2002-05-30 | — | — | WO | claimed |
| CN-114763346-B | Compounds for inducing cartilage formation and application thereof | 华东师范大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-114763346-A | Compound for inducing chondrogenesis and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |