Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | KDR | P35968 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | PTGES | O14684 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | PLEC | Q15149 | 1/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30733219 | 1.00 | MAPT (0.68) | MAPTSMN1; SMN2KDM4EKDRMEN1 | |
| SCHEMBL3039060 | 0.90 | KDM4E (0.61) | MAPTSMN1; SMN2KDM4EKDRMEN1 | |
| SCHEMBL1507696 | 0.83 | MAPT (0.78) | MAPTSMN1; SMN2KDM4EKDRMEN1 | |
| SCHEMBL28199290 | 0.83 | KDM4E (0.73) | MAPTSMN1; SMN2KDM4EKDRMEN1 | |
| SCHEMBL29831327 | 0.82 | MAPT (0.70) | MAPTSMN1; SMN2MEN1KMT2APTGES | |
| SCHEMBL17552188 | 0.82 | MAPT (0.70) | MAPTSMN1; SMN2MEN1KMT2APTGES | |
| SCHEMBL6537870 | 0.82 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2KDM4EKDRPTGES | |
| SCHEMBL3088776 | 0.82 | NPC1 (0.55) | SMN1; SMN2KDM4EKDRMEN1KMT2A | |
| SCHEMBL7686467 | 0.81 | EGLN1 (0.66) | MAPTSMN1; SMN2KDM4EKDR | |
| SCHEMBL19422863 | 0.81 | MAPT (1.00) | MAPTSMN1; SMN2KDM4EKDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021160-B1 | CARBOXYMIDE AND ANILINE DERIVATIVES AS SELECTIVE INHIBITORS OF PATHOGENS | AXXIMA PHARMACEUTICALS AG (DE) | 2002-05-30 | — | — | WO | claimed |
| CN-117945998-A | Ortho-selective deuteration method for aromatic amide compounds | 浙大宁波理工学院 | 2024-04-30 | — | — | CN | disclosed |
| CN-117486795-A | Preparation method of deuterated amide aromatic compound | 浙大宁波理工学院 | 2024-02-02 | — | — | CN | disclosed |